Starting Dose: 0.25mg
The introductory dose allows your body to adjust gradually, minimizing GI side effects.
Your Trusted Restore Wellness Clinic Waco, Texas
FDA-approved Semaglutide (Ozempic / Wegovy) is the most extensively studied GLP-1 weight loss medication in history backed by landmark clinical trials and millions of patients worldwide. Available at Restore Wellness Clinic in Waco, Texas.
Avg. Body Weight Reduction
Patients Achieved ≥5% Weight Loss
STEP-1 Trial Duration
Simple Weekly Injection
The Science
Semaglutide is a once-weekly injectable medication developed by Novo Nordisk and FDA-approved for chronic weight management in 2021. It belongs to the class of medications known as GLP-1 receptor agonists — mimicking the GLP-1 hormone that your gut naturally releases after eating to signal fullness and regulate appetite.
You may recognize it by its brand names: Ozempic® (originally approved for type 2 diabetes at lower doses) and Wegovy® (approved specifically for obesity and weight management at the higher 2.4mg dose). At Restore Wellness Clinic, we prescribe Semaglutide as part of a fully supervised, individualized weight loss program.
Semaglutide activates GLP-1 receptors in the hypothalamus, directly reducing hunger signals and food cravings at the neurological level.
Slows the rate at which the stomach empties, keeping you fuller for longer after meals and reducing overall caloric intake.
Stimulates insulin secretion in response to food while suppressing glucagon, stabilizing blood sugar and improving metabolic health.
Both contain the same active ingredient Semaglutide but are approved for different indications and at different doses:
Brand
Originally FDA-approved for type 2 diabetes. Often prescribed off-label for weight loss at lower doses. Weekly subcutaneous injection.
Brand
FDA-approved specifically for chronic weight management in adults with obesity or overweight. The dose used in STEP trials.
Clinical Evidence
Semaglutide’s clinical evidence base is the most extensive of any weight loss medication ever approved with a comprehensive Phase 3 trial program spanning thousands of patients across multiple conditions.
Average body weight reduction with Semaglutide 2.4mg — STEP-1 Trial (68 weeks)
Of patients achieved at least 5% weight loss
Of patients achieved at least 10% weight loss
Major STEP Phase 3 trials most comprehensive weight loss evidence base
The STEP (Semaglutide Treatment Effect in People with obesity) program comprised four Phase 3 randomized controlled trials. STEP-1 enrolled 1,961 adults with obesity or overweight and at least one weight-related comorbidity. Participants received once-weekly Semaglutide 2.4mg alongside lifestyle intervention over 68 weeks. The results established Semaglutide as a landmark advancement in obesity pharmacotherapy — and remain the most cited weight loss clinical trial data in medical literature. Additional STEP trials evaluated Semaglutide in patients with type 2 diabetes, cardiovascular disease, and with/without intensive behavioral therapy. *Individual results vary. Results shown reflect published clinical trial averages with lifestyle intervention.
Semaglutide (Wegovy®) is FDA-approved for chronic weight management in adults with obesity (BMI ≥30) or overweight (BMI ≥27) with at least one weight-related comorbidity. Always consult a qualified provider before starting any medication.
Your Program
From your first consultation to lasting results a clear, provider-guided 4-step process with support at every stage.

Your provider reviews your health history, current medications, and goals to confirm Semaglutide is the right fit. Lab work may be ordered to establish your metabolic baseline.

A customized titration schedule is built around your body starting at 0.25mg and advancing gradually based on your tolerance and response. No rushed escalations.

You receive your medication with clear injection instructions, side effect guidance, and direct access to our team for any questions during the adjustment period.

Regular provider check-ins track your progress, manage side effects, and adjust your dose as needed. Your provider stays engaged throughout your entire program.
Dosing Schedule
A realistic look at what your first months on a GLP-1 program typically look like so you know exactly what you’re signing up for.
The introductory dose allows your body to adjust gradually, minimizing GI side effects.
Appetite suppression begins here. Provider reviews tolerability before next step.
Weight loss accelerates. Hunger and cravings reduce significantly.
Continued dose escalation with consistent weight loss results.
FDA-approved dose. Provider determines optimal maintenance level.
The slow titration schedule for Semaglutide is the most effective way to minimize side effects while allowing your body to build tolerance and appetite suppression progressively. We never rush this process.
Your provider will not escalate your dose until you’ve tolerated your current dose comfortably. If you’re achieving excellent results at a lower dose there’s no clinical reason to go higher. Our goal is your success, not a maximum prescription
Self-administered using a small, thin auto-injector pen into the abdomen, thigh, or upper arm. Our team provides full training — most patients adapt within a week.
Semaglutide must be refrigerated (36°F–46°F). Pens can be kept at room temperature for up to 56 days once opened. We provide complete instructions at your first visit.
Have a question or concern between appointments? Our clinic team is available. You are never managing this program alone.
Is This Right For You?
Our medically supervised programs are designed for individuals looking for safe, effective, and personalized weight management solutions.
Semaglutide is FDA-approved for adults with a BMI of 30 or higher as part of a physician-supervised chronic weight management program.
Patients with hypertension, high cholesterol, sleep apnea, or type 2 diabetes alongside overweight are strong candidates for Semaglutide treatment.
Semaglutide has the most extensive real-world safety data of any weight loss medication available — years of post-market surveillance across millions of patients worldwide.
Semaglutide was originally developed for blood sugar management — making it particularly beneficial for patients with metabolic conditions alongside weight goals.
The best outcomes come from following your provider’s complete program medication, nutritional guidance, and check-ins work together. Commitment is the foundation.
Your provider will screen for contraindications during your consultation. Semaglutide is not appropriate if you have:
The only way to know for sure is to speak with our provider. Consultations are straightforward and designed to give you honest, personalized guidance.
Beyond the Scale
Semaglutide’s benefits extend far beyond the number on a scale it creates meaningful improvements across your metabolic and overall health.
Average 14.9% body weight reduction over 68 weeks in landmark STEP trials. For a 200lb person, that’s nearly 30lbs on average with 69% of patients achieving 10% or greater reduction.
Semaglutide acts directly on hunger-regulating centers in the brain, reducing both appetite and food cravings. Patients frequently describe a fundamental shift in their relationship with food.
Originally developed for type 2 diabetes, Semaglutide is highly effective at improving insulin sensitivity and stabilizing blood sugar making it especially valuable for patients with metabolic conditions.
The SELECT trial demonstrated a 20% reduction in major cardiovascular events with Semaglutide even independent of weight loss. This makes it uniquely valuable for patients with cardiovascular risk factors.
The SELECT trial demonstrated a 20% reduction in major cardiovascular events with Semaglutide even independent of weight loss. This makes it uniquely valuable for patients with cardiovascular risk factors.
As weight decreases, energy levels, joint health, sleep quality, and physical capacity all typically improve. Patients describe feeling more active, mobile, and capable in daily life.
Semaglutide has been prescribed to millions of patients globally since 2017. Its safety profile is more thoroughly understood than any other weight loss medication providing exceptional confidence for long-term use.
Medication Comparison
We are not a one-size-fits-all clinic. Every patient receives individualized care, evidence based treatment and genuine provider support from day one to long term success.
| Factor | Semaglutide We Offer | Tirzepatide |
|---|---|---|
| Mechanism | GLP-1 only | Dual GIP + GLP-1 |
| Avg. Weight Loss | Up to 14.9% | Up to 22.5% |
| FDA Approval (Obesity) | 2021 — 3+ years data | 2023 |
| Long-Term Safety Data | Most extensive available | Growing rapidly |
| Cardiovascular Data | SELECT trial — 20% CV risk ↓ | Trials ongoing |
| Blood Sugar Control | Proven in diabetes (SUSTAIN) | Stronger effect |
| Dosing | Once weekly | Once weekly |
While Tirzepatide produces greater average weight loss, Semaglutide has distinct advantages that make it the preferred choice for many patients. It has been prescribed globally since 2017, giving it years of extensive real-world safety observation that no newer medication can match.
For patients with established cardiovascular disease or risk factors, Semaglutide’s SELECT trial data showing a 20% reduction in major cardiovascular events provides a level of confidence that is uniquely compelling. For patients with type 2 diabetes, Semaglutide’s deep history in that indication offers additional clinical backing.
Some patients also simply prefer a medication with the most thoroughly understood long-term profile. Both medications are excellent. Your provider will recommend the most appropriate option based on your individual health picture, goals, and preferences.
What to Know
Semaglutide is well-tolerated by most patients. Thanks to its extended safety record, side effects are well-characterized and manageable with the right approach.
Typically mild and most pronounced in the first 1–4 weeks at each new dose level. Significantly reduced by the slow titration protocol and dietary modifications.
An expected and desired effect Semaglutide is working when you feel less hungry. This is the primary mechanism driving weight loss and not a concern.
Diarrhea, constipation, bloating, or stomach discomfort may occur in early weeks. These effects are well-documented in clinical literature and typically transient
Mild redness or discomfort at the injection site is possible. Rotating injection sites reduces this. Most patients experience no significant injection site issues.
Starting at 0.25mg and advancing only every 4 weeks gives your body maximum time to adapt. This protocol dramatically reduces side effect severity versus aggressive dosing.
Smaller, more frequent meals and reducing high-fat foods significantly reduces nausea. Our team provides specific practical guidance for the first weeks of treatment
Adequate hydration supports gastrointestinal comfort throughout treatment. We provide a practical hydration strategy alongside your medication instructions.
Side effects that become difficult to manage should be reported promptly. We can pause titration, adjust your dose timing, or recommend additional supportive care.
Backed by years of clinical evidence and a safety record no other weight loss medication can match Semaglutide at Restore Wellness Clinic is a proven, physician-supervised path to meaningful, lasting results.
Semaglutide is a GLP-1 receptor agonist it mimics the GLP-1 hormone your gut naturally produces after eating to signal fullness. It suppresses appetite by acting on hunger centers in the brain, slows gastric emptying to keep you feeling fuller longer, and improves blood sugar control by stimulating insulin release. The STEP-1 trial demonstrated an average 14.9% body weight reduction over 68 weeks. It is available under the brand names Ozempic® and Wegovy®.
The STEP-1 Phase 3 clinical trial showed an average body weight reduction of 14.9% over 68 weeks with Semaglutide 2.4mg. 86% of patients achieved at least 5% weight loss, and 69% achieved at least 10%. Individual results depend on adherence to your provider’s complete program — including medication, nutritional guidance, and follow-up check-ins. Results are not guaranteed and vary by individual.
Yes. Restore Wellness Clinic in Waco, Texas offers physician supervised Semaglutide weight loss programs for eligible patients. We serve patients throughout Waco and Central Texas. To get started, book a consultation through our Tebra patient portal using the form on this page.
Both Ozempic® and Wegovy® contain Semaglutide — the same active ingredient. Ozempic (0.5mg–2mg) is FDA-approved for the treatment of type 2 diabetes and is sometimes prescribed off-label for weight loss. Wegovy (2.4mg) is FDA-approved specifically for chronic weight management in adults with obesity or overweight. The higher dose in Wegovy is what was used in the STEP clinical trials producing 14.9% average weight loss. Your provider will determine the appropriate formulation and dose for your needs.
This is best determined during your consultation with our provider. Tirzepatide produces greater average weight loss (up to 22.5% vs. 14.9%) due to its dual GIP/GLP-1 mechanism. Semaglutide has a longer safety track record, extensive cardiovascular outcome data (20% CV risk reduction in SELECT trial), and a deeper evidence base in type 2 diabetes management. Some patients prioritize maximum weight loss results; others prioritize the most thoroughly studied long-term safety profile. Your provider will recommend the best option based on your health history, goals, and individual needs.
Semaglutide is administered as a once-weekly subcutaneous injection using a pre-filled auto-injector pen. Injections are self-administered into the abdomen, thigh, or upper arm. Our team provides thorough training at your first visit — the pen is designed for ease of use and most patients become comfortable within a week or two.
The most common side effects are gastrointestinal nausea, mild stomach discomfort, and reduced appetite. These are most common during the early weeks and at each dose escalation step. The gradual titration protocol (starting at 0.25mg) significantly reduces their severity. Most patients find that side effects diminish substantially within 4–8 weeks as their body adapts. Dietary modifications and our team’s guidance help most patients move through the adjustment period comfortably.
All appointments at Restore Wellness Clinic are booked through our secure Tebra patient portal. Submit your information on this page and our team will contact you within 24 hours to confirm your appointment and send portal access for completing your intake forms ahead of your visit.
Visit our Restore Wellness Clinic for personalized care and wellness services. Our team is here to support your health journey in a comfortable and welcoming environment.
No obligation. We’ll reach out within 24 hours to confirm your appointment.
Semaglutide is not a trend it’s one of the most studied and trusted weight loss medications ever developed. With physician supervision, a personalized dosing protocol, and the strongest long-term safety data in the field, Restore Wellness Clinic is ready to help you achieve results that last.